The recognition and significance of workplace spirituality in contemporary organizational settings have grown considerably, reflecting a paradigm shift in which employees increasingly expect meaningful work and a sense of community alongside conventional monetary and non-monetary benefits. Workplace spirituality has emerged as an effective mechanism for inducing organizational commitment, job involvement, creativity, and innovation, while simultaneously reducing employee turnover intentions. This growing relevance has attracted researchers worldwide, with several Western studies examining the components and effects of workplace spirituality on employee performance. The purpose of the present research is to investigate the mediating effect of employee commitment, employee engagement, and work motivation in the relationship between workplace spirituality and organizational performance within the Indian context. Using standardized self-report measures and a systematic literature review guided by the PRISMA 2020 framework, this study analyzes approximately 120 peer-reviewed papers published between 2020 and 2024. The findings were synthesized into four themes, namely workplace spirituality and employee well-being, spiritual leadership and organizational performance, workplace spirituality and employee engagement or motivation, and religiosity, spirituality, and employee experiences. The results indicate that a majority of the reviewed studies demonstrate a positive correlation between workplace spirituality practices and employee well-being metrics, and that affective and normative commitment, employee engagement, and work motivation partially mediate the spirituality–performance relationship, thereby reinforcing the strategic significance of organizational spirituality