This study examines the adoption of Electronic Customer Relationship Management (E-CRM) systems among Small and Medium-sized Enterprises (SMEs) in developing economies. It highlights the potential of E-CRM to improve customer relationships, streamline business operations, and support sustainable growth, while also identifying major challenges affecting successful implementation. Using a mixed-methods approach, quantitative data were collected from 500 SMEs across multiple sectors and analyzed using SPSS and R. The findings reveal that government support, affordable technology access, and customized training programs significantly influence E-CRM adoption. The study provides valuable insights and practical recommendations for policymakers, technology providers, and SME entrepreneurs to enhance effective E-CRM implementation in emerging markets