Workplace stress has become a pervasive challenge affecting employee well-being, productivity, and organizational performance. In recent years, spirituality—distinct from religious affiliation—has emerged as a powerful resource for enhancing emotional balance, resilience, and workplace harmony. This study examines the impact of workplace spirituality on stress reduction, emphasizing mindfulness practices and harmony-oriented behaviours. Drawing from theoretical foundations and empirical insights, the paper evaluates how mindfulness, meaning-oriented work values, compassion, and interpersonal harmony contribute to employees’ ability to cope with high-pressure environments. The findings reveal that spirituality significantly reduces stress by facilitating self-awareness, promoting emotional regulation, fostering positive relationships, and creating a supportive organizational climate. The paper concludes that integrating spiritual well-being practices into organizational culture can enhance workforce morale, mental health, and overall productivity