This study explores how the entrepreneurial ecosystem in Kamrup, Assam influences the growth and empowerment of women entrepreneurs in a region rich in both opportunity and cultural complexity. Despite a nationwide rise in women-led ventures, systemic hurdles—such as restricted access to finance, limited mentorship, policy gaps, and social norms—continue to hinder progress. By adopting a mixed-methods approach, the research blends quantitative survey data with qualitative interviews from women entrepreneurs, policymakers, and support organizations like ASRLM and NERAMAC. Guided by Isenberg’s entrepreneurial ecosystem model, the study assesses core factors such as financial accessibility, institutional support, policy implementation, market access, and gendered cultural dynamics. While national initiatives like PMMY and Start-Up India have made inroads, persistent challenges like digital illiteracy and weak grassroots execution remain. Notably, the study highlights the promise of local solutions—such as women-led cooperatives and microfinance programs—when backed by coordinated and inclusive policies. This paper offers a regionally grounded intervention framework and stresses the importance of collaborative action across sectors to build a resilient, gender-sensitive ecosystem. It urges a shift from symbolic support to substantive, long-term empowerment for women entrepreneurs, positioning Kamrup as a potential model for inclusive entrepreneurial development in India